To clone T, you could in principle create a ____(1)____ from ____(2)____ cells, transform it into ____(3)____ cells, and grow those cells in medium supplemented with ____(4)____. Fill in the blanks: Blank 1 can be filled with: (SELECT ALL THAT APPLY)1. Genomic DNA librarycDNA library2. antibiotic-sensitive cellsantibiotic-resistant cells3. antibiotic-resistant cellsantibiotic-sensitive cells4. tetrahydrofolate and NO antibioticantibiotic and tetrahydrofolateantibiotic and NO tetrahydrofolateNO antibiotic and NO tetrahydrofolate



Answer :

Antimicrobial resistance mechanisms fall into four main categories: (1) limiting uptake of a drug; (2) modifying a drug target; (3) inactivating a drug; (4) active drug efflux

Antibacterial medications are degraded by enzymes, bacterial proteins that are targets for antibiotics are changed, and membrane permeability to antibiotics is altered. These three processes constitute the three basic mechanisms of antimicrobial resistance. methicillin-resistant A. Staphylococcus (MRSA) vancomycin-resistant Enterococcus (VRE) (VRE) Drug-resistant infections are mostly brought on by the improper use and abuse of antibiotics. The proliferation of bacteria, some of which may be resistant to antibiotic therapy, is encouraged by a lack of clean water, proper sanitation, and effective infection prevention and control. Penicillins, fluoroquinolones, cephalosporins, macrolides, beta-lactams with increased activity (like amoxicillin-clavulanate), tetracyclines, trimethoprim-sulfamethoxazole, lincosamides (like clindamycin), urinary anti-infectives, and other antibiotics are all classified as one of these classes in this portal.

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