Why is it thought that glycolysis is the first catabolic pathway to have evolved in the metabolism of all cellular systems?
Glycolysis produces much less ATP than does oxidative phosphorylation. Glycolysis takes place in the cytosol, does not involve oxygen, and is present in most organisms. It is found in prokaryotic cells but not in eukaryotic cells. Glycolysis is the first step that breaks down glucose and MUST be done before any further metabolic pathways can break down the glycolysis products. Glycolysis occurs in the cytoplasm which mean it would have been able to be used before the bacteria that formed the mitochondria invade the cell that gave rise to all eukaryotes, indicating it must have been a very fundamental early pathway. Glycolysis does not require any of the membrane-bound organelles of the eukaryotic cell which evolved approximately 1 billion years after the prokaryotic cells. Before there was oxygen in the earth's atmosphere, there was only anaerobic processes - So they must have developed first. The primary method for anaerobic bacteria is glycolysis because it provides energy without oxygen. Aerobic processes require a huge number of specific proteins, whereas glycolysis has a minimal number of proteins involved. The oldest known fossils of bacteria date back 3.5 billion years when appreciable quantities of oxygen were not accumulated in the atmosphere -- so therefore since glycolysis does not require Oxygen and is thought to be the first catabolic pathway to have evolved.

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09-12-2022
Biology

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Why is it thought that glycolysis is the first catabolic pathway to have evolved in the metabolism of all cellular systems?
Glycolysis produces much less ATP than does oxidative phosphorylation. Glycolysis takes place in the cytosol, does not involve oxygen, and is present in most organisms. It is found in prokaryotic cells but not in eukaryotic cells. Glycolysis is the first step that breaks down glucose and MUST be done before any further metabolic pathways can break down the glycolysis products. Glycolysis occurs in the cytoplasm which mean it would have been able to be used before the bacteria that formed the mitochondria invade the cell that gave rise to all eukaryotes, indicating it must have been a very fundamental early pathway. Glycolysis does not require any of the membrane-bound organelles of the eukaryotic cell which evolved approximately 1 billion years after the prokaryotic cells. Before there was oxygen in the earth's atmosphere, there was only anaerobic processes - So they must have developed first. The primary method for anaerobic bacteria is glycolysis because it provides energy without oxygen. Aerobic processes require a huge number of specific proteins, whereas glycolysis has a minimal number of proteins involved. The oldest known fossils of bacteria date back 3.5 billion years when appreciable quantities of oxygen were not accumulated in the atmosphere -- so therefore since glycolysis does not require Oxygen and is thought to be the first catabolic pathway to have evolved.

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kumarravichandra kumarravichandra · Answer 1 · 2022-12-16T03:14:34-05:00

Nearly all sorts of organisms have evolved a metabolic process and anaerobic energy source called glycolysis. The Embden-Meyerhof pathway is another name for the process, given in honour of the key figures in its discovery and comprehension.

It serves a purpose in anaerobic respiration because it doesn't need oxygen, but it is also the initial stage in cellular respiration. Molecules of glucose, the most important organic fuel for plants, microorganisms, and animals, are oxidised during the process. a majority of cells favour glucose Per glucose molecule, glycolysis uses up 2 ATP molecules and generates 4 ATP, 2 NADH, and 2 pyruvates. The citric acid cycle or other processes can both employ pyruvate as a precursor.In the end, glycolysis divides glucose into two pyruvate molecules. Glycolysis can be thought of as having two stages that take place in the cytosol of cells. Due to the use of two ATP molecules, the first phase is known as the "investment" phase, while the second is known as the "payoff" phase. Each of these processes is performed by a different enzyme, with phosphofructokinase serving as the most crucial regulator because it regulates the rate of glycolysis.

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