Answer :

Events in activation of a b cell by a microbe in the order

1) A mature B cell expresses a particular type of B cell receptor on its cell membrane after differentiating from a lymphocyte stem cell.

2) The B cell's gene expression is changed, and the B cell starts to divide.

3) After several cycles of cell division, a large number of B cells bearing the same B cell receptor are created.

4) A foreign antigen is bound by the BCR (B cell receptor) of the B cell with high specificity and high affinity.

5) The B cell's second messenger signaling is turned on.

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