When acetylcholine binds to its receptors on the motor end plate, an ion channel opens and sodium ions diffuse quickly into the muscle cell.
Acetylcholine tends to glue to the nicotinic receptors concentrated on the motor end plate, a particular region of the post-synaptic membrane of the muscle fiber.
Therefore, The nicotinic receptor channels open as a result of this interaction, allowing sodium ions to enter the muscle fiber. The geometry of the whole receptor is slightly altered when acetylcholine binds to these two chains, opening the channel.
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