Using sickle cell anemia as an example, discuss how mutations, genetics, and evolution interact in real life situation. Describe the genetics of sickle cell anemia, how the sickle allele originated, and describe the TWO main natural selective pressures acting on the hemoglobin gene in different environments. Why hasnt the sickle allele died out? Combine your knowledge of genetics and evolution in discussing this. Does your answer suggest that humans are still evolving?