Which of the following statements is true regarding the chemiosmotic coupling between mitochondrial ATP synthesis and electron flow through the respiratory chain?
a. Inhibition of electron flow inhibits mitochondrial ATP synthesis, and inhibition of mitochondrial ATP synthesis inhibits electron flow.
b. Inhibition of electron flow does not inhibit mitochondrial ATP synthesis, and inhibition of mitochondrial ATP synthesis does not inhibit electron flow.
c. Inhibition of electron flow inhibits mitochondrial ATP synthesis, but inhibition of mitochondrial ATP synthesis does not inhibit electron flow.
d. Inhibition of electron flow does not inhibit mitochondrial ATP synthesis, but inhibition of mitochondrial ATP synthesis inhibits electron flow.

Question

05-12-2022
Biology

Answered

Which of the following statements is true regarding the chemiosmotic coupling between mitochondrial ATP synthesis and electron flow through the respiratory chain?
a. Inhibition of electron flow inhibits mitochondrial ATP synthesis, and inhibition of mitochondrial ATP synthesis inhibits electron flow.
b. Inhibition of electron flow does not inhibit mitochondrial ATP synthesis, and inhibition of mitochondrial ATP synthesis does not inhibit electron flow.
c. Inhibition of electron flow inhibits mitochondrial ATP synthesis, but inhibition of mitochondrial ATP synthesis does not inhibit electron flow.
d. Inhibition of electron flow does not inhibit mitochondrial ATP synthesis, but inhibition of mitochondrial ATP synthesis inhibits electron flow.

Answer :

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akursharma9034 akursharma9034 · Answer 1 · 2022-12-08T22:10:24-05:00

Inhibition of electron flow inhibits mitochondrial ATP synthesis, and inhibition of mitochondrial ATP synthesis inhibits electron flow. The difference in hydrogen ion concentration between the matrix of actively respiring mitochondria and the intermembrane space is the foundation of the chemiosmotic coupling mechanism.

The potential energy of the proton gradient that has formed between the inter-membrane space and matrix of the mitochondria is the immediate energy source that propels ATP synthesis by ATP synthase during oxidative phosphorylation. The pumping of protons that occurs along with the exchange of electrons is what produces the hydrogen ion gradient.

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