multiple select question select all that apply chargaff found that double-stranded dna contains approximately a 1:1 ratio of adenine and thymine, and approximately a 1:1 ratio of cytosine and guanine. what did james watson conclude from this observation? multiple select question. that cytosine in one strand of dna binds to adenine in the other strand that adenine in one strand of dna binds to thymine in the other strand that cytosine in one strand of dna binds to guanine in the other strand that thymine in one strand of dna binds to guanine in the other strand that dna is replicated in a semiconservative way