Answer :
- Increased gastric pH
- Delayed gastric emptying
- Faster intramuscular absorption
Neonate's body's natural defense flaws have been highlighted as potential contributing reasons in neonates' exceptional susceptibility to serious and dangerous bacterial infections.
Gastric pH is more than 2 at birth and falls when the stomach starts to release acid. According to the majority of research, acid secretion rises from birth until day 10, then drops over the following 20 days.
Neonatal blood PMNs are aberrant in both quantity and quality, and these abnormalities may be linked to the higher incidence, morbidity, and mortality of bacterial infections.
Due to the fact that their small neutrophil storage capacity, which may be quickly exhausted, and also because they have a qualitative deficiency in neutrophil activity, newborns are particularly vulnerable to bacterial and fungal infection.
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