Answer :
Transcription of the lac operon is high when all of the conditions necessary for gene expression are present.
For example, the presence of the inducer lactose would allow the repressor protein to be released from the operator (O), which would then allow RNA polymerase (RNAP) to bind to the promoter (P) and initiate transcription. The diagram below illustrates this state of the operon when transcription is high.When the lac operon is completely shut down, the repressor protein must be bound to the operator, preventing RNA polymerase from binding to the promoter and transcription from occurring. In addition, the inducer lactose must be absent so that the repressor protein can bind to the operator. The diagram below illustrates this state of the operon when transcription is completely shut down.
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