Hormones that govern calcium transport in the stomach, kidneys, and bone maintain calcium homeostasis.
The three target organs are also engaged in calcium homeostasis maintenance: the gut, kidney, and bone. These are the organs that calciotropic hormones directly or indirectly target.
The endocrine system is in charge of maintaining blood calcium homeostasis. The parathyroid and thyroid glands have receptors that respond to calcium levels in the blood. The variable in this feedback loop is blood calcium level, which fluctuates in reaction to the environment.
Bidirectional calcium fluxes govern calcium homeostasis at the gut, bone, and kidney levels. The latter organ is crucial in controlling extracellular calcium concentrations.
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