Which of the following is true of osteoclasts?
A) Osteoclasts maintain protein and mineral content of matrix.
B) Osteoclasts are responsible for laying down osteoid.
C) Osteoclasts form cytoplasmic extensions within canaliculi.
D) Osteoclasts are located within lacunae.
E) Osteoclasts secretes protein digesting enzymes and acids that dissolve matrix.

Question

19-12-2022
Biology

Answered

Which of the following is true of osteoclasts?
A) Osteoclasts maintain protein and mineral content of matrix.
B) Osteoclasts are responsible for laying down osteoid.
C) Osteoclasts form cytoplasmic extensions within canaliculi.
D) Osteoclasts are located within lacunae.
E) Osteoclasts secretes protein digesting enzymes and acids that dissolve matrix.

Answer :

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jaspreetsharma jaspreetsharma · Answer 1 · 2022-12-24T00:25:25-05:00

Protein-digesting enzymes & acids that disintegrate matrix are secreted by osteoclasts.

The implantation of osteoid is carried out by osteoclasts. The precursor tissue of bone tissue, called osteoid, is not laid down by osteoclasts. The cells known as osteoclasts mediate bone loss in pathologic conditions by increasing their resorptive activity and degrading bone to start normal bone remodeling. They originate from myeloid/monocyte lineage precursors that circulate in the blood after developing in the bone marrow. Osteoclasts are cells that break down bone. They may phagotize the deionised products and dead osteocytes, and they secrete lysosomal enzymes. It happens when Cathepsin K, an osteoclast-secreted proteinase that annihilates Type I collagen, undergoes genetic mutation. Therefore, osteoclasts are able to resorb the mineralized part of the bone matrix but not the non-mineralized section.

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