Answer :
the mesolimbic dopamine pathway consists of neurons from the ventral tegmental area to the nucleus accumbens. it plays an important role in nicotine addiction.
The reward pathway, also known as the mesolimbic pathway, is a dopaminergic pathway inside the brain. The pathway attaches the ventral tegmental area of the midbrain to the basal ganglia's ventral striatum in the forebrain. The nucleus accumbens and the olfactory tubercle are located in the ventral striatum.
Dopaminergic components from the ventral tegmental area (VTA) innervate areas of the brain engaged in executive, affective, and motivational functions, along with the prefrontal cortex (PFC), amygdala, and nucleus accumbens, in the mesolimbic system (NAc).
Addictions are caused by changes in the brain's mesolimbic dopamine pathway, also recognized as the reward circuit, which starts above the brain stem inside the ventral tegmental area (VTA).
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