Answer :

Tetracycline resistance is frequently caused by the acquisition of new genes that are responsible for energy-dependent tetracycline efflux or for a protein that safeguards bacterial ribosomes from tetracycline action.

Tetracycline belongs to a class of drugs known as tetracycline antibiotics. It operates by preventing bacterial growth and spread. Tetracycline and other antibiotics will not treat colds, flu, or other viral infections.

Tetracycline resistance gene tet(W) encrypts a protection protein that adheres to the ribosome and causes a change in the ribosomal conformation to which tetracycline cannot bind, allowing protein synthesis to proceed.

Tetracycline resistance is generally attributed to one or more of the following factors: the acquisition of mobile genetic elements containing tetracycline-specific resistance genes, mutations within the ribosomal binding site, and/or chromosomal mutations resulting in higher expression of intrinsic resistance mechanisms.

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