an intracellular acting bacterial toxin, whose a fragment is translocated through the endoplasmic reticulum (er) membrane into the cytosol of host cel

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12-12-2022
Biology

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an intracellular acting bacterial toxin, whose a fragment is translocated through the endoplasmic reticulum (er) membrane into the cytosol of host cel

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contexto1028 contexto1028 · Answer 1 · 2022-12-18T09:10:13-05:00

A-B toxins, which are the classic type III toxins, are made up of two parts: a "A" or active component that disrupts the function of a host cell by enzymatically inactivating a protein or signaling pathway; and a "B" or binding component that binds the exotoxin to a host-surface receptor molecule.

What functions is adenylate cyclase toxin?

Bordetella pertussis' adenylate cyclase toxin (CyaA) is an essential virulence factor for the initial stages of lung colonization. When activated by endogenous calmodulin, it can enter eukaryotic cells and cause levels of cAMP to become out of control.

Is botulinum toxin a toxin from AB?

The diphtheria toxin, the cholera toxin, the anthrax toxin, the Shiga toxin, and the botulinum toxin are all members of the AB toxins family [5, 6, 7, 8, 9].

To learn more about III toxins here:

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