The tryptophan operon is a repressible operon that is turned off whenever tryptophan is added to the growth medium.
The tryptophan operon is a collection of genes that are transcribed together and encode the enzymes that produce tryptophan in bacteria. The trp operon was discovered in many other bacteria after being discovered in Escherichia coli. The tryptophan binds to the trp repressor, causing it to change shape and become active (DNA-binding). The trp repressor attaches to the operator, preventing RNA polymerase from binding to the promoter and thus preventing operon transcription.
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