You believe that you have isolated a new strain of positive-sense, single-stranded RNA virus and set about studying it in your laboratory. Which of the following lines of evidence would most strongly support your hypothesis that the virus is a [+]ssRNA?
A) The virions are diploid.
B) You sequence the bases in the viral RNA and the mRNA and find them to be antiparallel.
C) Introducing a protease inhibitor causes the virus to stop producing proteins and reproducing.
D) Introducing a reverse transcriptase inhibitor slows down the growth of the virus.C) Introducing a protease inhibitor causes the virus to stop producing proteins and reproducing.



Answer :

OPTION C Introducing a protease inhibitor causes the virus to stop producing proteins and reproducing would most strongly support your hypothesis that the virus is a [+]ssRNA

Positive-strand or single strand RNA viruses (+ssRNA viruses) are a class of viruses with ribonucleic acid genomes that are positive-sense. The positive-sense genome can function as messenger RNA (mRNA) and be directly translated into viral proteins by the ribosomes of the host cell. Positive-strand RNA viruses encode an RNA-dependent RNA polymerase (RdRp), which is used during genome replication to generate a negative-sense antigenome, which is then used as a template to generate a new positive-sense viral genome. One type of antiretroviral drug used to treat HIV is protease inhibitors. The goal of these drugs is to reduce the amount of HIV virus in the body (known as the viral load) to undetectable levels. This slows the progression of HIV and aids in the treatment of symptoms.

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