Answer :
In the course of mitosis, microtubules connect to this region of the chromosome to transport sister chromatids to the cell poles.
Interpolar microtubules run from the spindle pole from across equator, nearly to the other spindle pole, whereas astral microtubules run from the spindle pole to the cell surface. Kinetochore microtubules bind the chromosomes to a spindle pole. The centromere, also known as the kinetochore, is a specific area on the surface of a chromosome where the microtubules are attached. Chromosomes can really be "trapped" on microtubules since they are constantly polymerizing and depolymerizing. Figure below depicts a spindle formed of microtubule-based fibers. Spindle. During the prophase of mitosis, the spindle begins to develop. Sister chromatid centromeres are connected to the spindle's kinetochores by the spindle..
(During mitosis, chromosomes are attached by their kinetochores to the microtubules of the spindle. In an 'amphitelic' attachment, the kinetochore (k)-fibre bundles of microtubules attach each sister kinetochore to opposite spindle poles (see part a in the figure).)
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