Answered

Which of the following best describes a biological concern regarding the use of CRISPR-Cas9 gene editing in humans?
A.The process was first discovered in bacteria and human cells cannot correctly interpret prokaryotic regulatory signals.
BThe modifications created by the process may result in unintended effects on non-target genes.
C. The presence of repeated sequences (STRs) within the human genome mean that the editing cannot be targeted to a specific location.
D. The process may introduce viral sequences into the human genome leading to unwanted blood cell proliferation (leukemia).



Answer :

CRISPR-Cas9 gene editing is a method to alter or change the human genome. Target genes are chosen and changed in this process. However, this modification may affect the non-targeted genes, and this is a serious biological concern.

DNA is altered by adding or removing a segment of the gene.  In this method, the targeted genes produce a specified product. The product will not be produced if in case the non-targeted genes get affected. In spite of this, the modifications created by the process may result in unintended effects on non-target genes.  

Therefore, the correct option is (B).

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