MrJonezy8169 MrJonezy8169

10-11-2022
Biology

Answered

what term would best describe the expression of the gal10 and gal1 genes in a strain that is gal80-?

Answer :

RajarshiG RajarshiG

22-11-2022

Best represents the expression of the gal10 and gal1 genes in a strain that constitutively expresses gal80

constitutively expresses gal80 and Saccharomyces cerevisiae GAL80 gene (SGDID:S000004515) is a negative regulator of the transcriptional activator GAL4 from Saccharomyces cerevisiae. Dimers of GAL80 bind to GAL4 dimers, allowing GAL4 to bind UAS sequences but not to activate transcription (adapted from FBrf0233764). If GAL4 is the canonical on-switch for almost all transgenes of interest, GAL80 is the logical off-switch. GAL80 binds to the transcriptional activation domain of GAL4, thereby preventing recruitment of RNA polymerase (Ma and Ptashne 1987). Gal3 binds Gal80 more strongly than Gal1, indicating changes in adaptive proteins after replication. Molecular Biology and Evolution | Oxford Scholar.

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