The physical symptoms of cholera present only after a specific series of events has taken place. What is the most likely sequence of events in the pathogenesis of v. Cholerae?.



Answer :

Cholera is an infectious disease that occurs when it enters the body. This will have a series of symptoms after admission.

What are the symptoms that will occur?

The V. cholerae will be found in contaminated water that is ingested by the individual, if the V. cholerae survives it will pass from the stomach to the intestine and there it will adhere through the pili (which are its adhesins) and then begin to produce cholera toxins. This will cause the host cells to begin to break down, leading to severe diarrhea.

After dealing the damage, the v. cholerae will leave the host via feces. This will cause profuse dehydration in the individual which can lead to death.

It can also generate painful muscle cramps due to the loss of potassium that occurs thanks to profuse diarrhea.

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