Answer :
The final place in the nephron where there is the fine-tuning of water recovery or disposal occurs in collecting ducts and the Distal convoluted tubule.
The collecting duct (CD) and distal convoluted tubule (DCT) are the final two segments of the kidney nephron. They play a crucial role in the reabsorption of water and the absorption of numerous ions.
The proximal tubule and the descending limb of the loop of Henle re-absorb the majority of the fluid that is filtered at the glomerulus. The AQPs make it easier for the majority of the nephron's water reabsorption.
Other AQPs regulate water resorption in the distal tubule and collecting duct, with AQP2 and its interaction with arginine vasopressin (AVP) dominating. The kidneys are able to "fine tune" the body's water balance by controlling water resorption in the distal nephron, which receives only 15% of the filtrate. The hypertonic milieu of the medullary portion of the kidneys created by the active transport of sodium and urea from the lumen of the thick ascending loop of Henle into the interstitial space surrounding the collecting ducts is the osmotic driving force for the movement of water through the epithelia of the collecting ducts.
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