There is a ______- brain barrier that prevents harmful materials from the brain.

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09-11-2022
Biology

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There is a ______- brain barrier that prevents harmful materials from the brain.

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VTDK248 VTDK248 · Answer 1 · 2022-11-15T02:46:15-05:00

There is a barrier called Blood- Brain barrier that prevents harmful materials from the brain.

What is Blood-brain barrier ?

The Blood-Brain barrier (BBB) is a diffusion barrier, which obstruct flow of most compounds from blood to brain.

There are three cellular elements of the brain which are as follows

1.) Microvasculature which consist the BBB-endothelial cells

2) Astrocyte end-feet

3) Pericytes (PCs)

Tight junctions (TJs) which are present between the cerebral endothelial cells, acts as a diffusion barrier, which selectively excludes most blood-borne substances from entering the brain. Astrocytic end-feet tightly enfold the vessel wall and acts as a crucial part for maintenance of the TJ barrier, but astrocytes does not have a barrier function in the mammalian brain.

Dysfunction of the BBB, such as impairment of the TJ seal, complications of neurologic diseases like stroke and neuroinflammatory disorders.

Thus, there is a barrier called Blood- Brain barrier that prevents harmful materials from the brain.

Learn more about Blood-Brain barrier, here:

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