The two strands of a DNA double helix are antiparallel which means that they run alongside each other but point in opposite directions.
Antiparallel strands of a DNA molecule implies that the phosphate groups at the beginning of two DNA strands are in opposite positions.
The DNA molecule is made up of two strands bonded together by hydrogen bonds. A single strand is different at its two ends such that one end is called 5' and the other is called 3'. The names are derived from the notation for the two sugar carbon atoms which are present in the phosphodiester bonds.
The anti-parallel strands allow the formation of hydrogen bonds. If the strands are not antiparallel then non-symmetrical hydrogen bonding interactions is not possible. It is very important that CG interactions have three H- bonds and AT has two H-bonds.
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