Individuals with the disorder xeroderma pigmentosum are hypersensitive to sunlight. This occurs because their cells have which impaired ability?.

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08-11-2022
Biology

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Individuals with the disorder xeroderma pigmentosum are hypersensitive to sunlight. This occurs because their cells have which impaired ability?.

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contexto1005 contexto1005 · Answer 1 · 2022-11-14T08:04:59-05:00

Xeroderma pigmentosum (XP) is a rare, inherited disorder that affects the skin's ability to protect itself from the damaging effects of ultraviolet (UV) rays from the sun.

People with XP have a defect in a gene that is responsible for repairing DNA damage caused by UV exposure. As a result, their skin cells are unable to repair the DNA damage, which leads to the development of skin cancer.

Xeroderma pigmentosum XP is divided into two types, depending on the severity of the condition. Type I is the most severe form and is characterized by photosensitivity, which is an extreme sensitivity to sunlight. People with type I XP often develop skin cancer at an early age. Type II is less severe and is characterized by a milder form of photosensitivity. People with type II XP may develop skin cancer, but it is usually not as early as those with type I.

There is no cure for Xeroderma pigmentosum XP, but there are treatments that can help to protect the skin from the harmful effects of sunlight. These include the use of sunscreen, avoiding sun exposure, and wearing protective clothing.

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