Answer :
Two properties of glucokinase are its functions as the beta cell's glucose sensor by controlling the rate of glucose entry into the glycolytic pathway and subsequent metabolism.
It is well capable of insulin stimulation release from the pancreas. Particularly in the postprandial phase, glucose kinase is crucial for the liver's ability to store glucose as glycogen. High glucokinase activity is essential for postprandial glucose phosphorylation, metabolic signal synthesis in glucose-induced insulin secretion in beta cells, and the storage of glucose as glycogen in the liver.
Glucokinase is referred to as the "glucose sensor of the beta-cell" due to its strict control over the release of insulin. As a result, early in the disease, hyperinsulinemia may be brought on by excessive glycolysis, which can be reduced to restore the normal stimulus-secretion coupling.
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