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In the example in the animation, uracil is incorrectly paired with guanine. What is the effect on the dna sequence if base excision repair does not remove the uracil and dna replication is allowed to proceed?



Answer :

Mutation will occur  in the DNA sequence if base excision repair does not remove the uracil and DNA replication is allowed to proceed.

What occurs when DNA damage is not repaired prior to replication?

DNA's stability and integrity are crucial to life since it houses each live cell's genetic information. However, DNA is not inert; rather, it is a chemical structure that can be harmed by the environment. If the damage is not repaired, it can result in mutation and even disease.

What occurs if nucleotide excision repair is unsuccessful?

Base excision repair (BER) is in charge of repairing broken DNA bases, including those left over after oxidative damage, deamination, and SSBs. Point mutations may occur as a result of these lesions not being repaired.

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