gpi-anchoring serves a special function, especially in polarized epithelial cell because this modification serves to target proteins to the RER (rough endoplasmic reticulum).
what is RER?
Rough endoplasmic reticulum (RER), a network of interconnected flattened sacs that is an organelle with a continuous membrane found in the cytoplasm of eukaryotic cells and is essential for protein production.
The RER is linked to numerous functions in protein production, including sorting, folding, and post-translational modifications. The mature