how many different types of subunits are there in bacterial rnap holoenzyme and what are their names?

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08-11-2022
Biology

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how many different types of subunits are there in bacterial rnap holoenzyme and what are their names?

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contexto115 contexto115 · Answer 1 · 2022-11-14T07:48:51-05:00

There are five different types of subunits are there in bacterial RNAP holoenzyme.

The Escherichia coli RNA polymerase (RNAP) is a multi-subunit enzyme composed of five subunits including α (two copies), β, β’ and ω subunits. These five subunits form the RNAP core enzyme responsible for RNA synthesis using DNA as template and ribonucleotide (rNTP) as substrate. For initiating promoter specific DNA transcription, the core enzyme has to bind a σ factor, which helps to direct the polymerase to specific promoters. The core polymerase with sigma factor is referred to as the holoenzyme.

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