Answer :
When the wrong blood type is given to a patient, the antibodies in the patients' blood react with the antigens on the surface of the transfused blood causing a reaction called agglutination.
Days or even weeks after receiving blood transfusions, patients may experience delayed hemolytic responses. These reactions are brought on by previously developed antibodies in the patient that react with antigens on the donor cells' surface. Agglutination is the process by which specific antibodies to antigenic components on the surface of red blood cells or inert particles (direct agglutination) or to antigenic components adsorbed or chemically attached to these cells or particles produce clumps of cells or inert particles. IgM and IgA antibodies, which have many reactive Fab sites, are primarily responsible for agglutination. In order to more efficiently phagocytose germs, the Fab part of the antibodies joins (causes them to agglutinate) bacteria together.
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