mature t cells have t-cell receptors that can bind only to the particular self-mhc isoform that provided the signal for survival during t-cell development. what is this called?

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04-11-2022
Biology

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mature t cells have t-cell receptors that can bind only to the particular self-mhc isoform that provided the signal for survival during t-cell development. what is this called?

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AnnuG AnnuG · Answer 1 · 2022-11-07T23:02:23-05:00

Mature T cells have T-cell receptors that can bind only to the particular self-MHC isoform that provided the signal for survival during T-cell development. This is called MHC restriction.

T cells are the lymphocytes that are synthesized in the bone marrow but develop in the thymus. T cells are critical in providing specific immunity to the cells and hence belong to the adaptive immunity. There are two types of T cells: Helper T cells and Cytotoxic T cells.

MHC is the abbreviation for Major Histocompatibility Complex. They are helpful in recognizing the foreign substances present inside the body. They play role in antigen recognition by presenting the antigenic peptides to the T cell receptor.

To know more about MHC, here

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