a cell can form 10 nm chromatin fibers, but not 30 nm fibers. which molecule has likely been removed or mutated in this cell?

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04-11-2022
Biology

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a cell can form 10 nm chromatin fibers, but not 30 nm fibers. which molecule has likely been removed or mutated in this cell?

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AnnuG AnnuG · Answer 1 · 2022-11-08T01:59:01-05:00

The linker histone (H1) has likely been removed or mutated in the cell that can form 10 nm fiber but not 30 nm fiber.

Linker histone is the H1 protein that is a key component for the formation of 30 nm chromatin fiber. It binds to the nucleosome core around the entry and exit of DNA. It is responsible for regulating the accessibility of DNA for the processes like replication or transcription.

30 nm fiber is one of the stage in the chromatic compaction. It comprises of a helical array of nucleosomes, where the core particle wraps 146-147 base pairs of DNA around it along with the linker histone. The length of this structure is 30 nm and hence the name.

To know more about linker histone, here

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