imagine a bacterial cell with a mutation that renders d n a pol i completely nonfunctional (note that this would be a lethal mutation). what, precisely, would go wrong with replication in this cell?

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04-11-2022
Biology

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imagine a bacterial cell with a mutation that renders d n a pol i completely nonfunctional (note that this would be a lethal mutation). what, precisely, would go wrong with replication in this cell?

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AnnuG AnnuG · Answer 1 · 2022-11-08T02:19:51-05:00

Upon DNA Pol I becoming completely non-functional, the RNA primers will not be replaced by DNA strands.

DNA Pol I is the Polymerase enzyme that has the role of DNA repair as sell as removal of RNA primers. It participates in prokaryotic replication. The enzyme is also known by the name Kornberg enzyme. It is also the first known DNA Polymerase enzyme.

RNA is the transcript formed from DNA. It is usually a single stranded molecule with nitrogenous bases cytosine, guanine, adenine and uracil. There are three major types of RNA: m-RNA, r-RNA and t-RNA. m-RNA is the coding RNA and also participates in replication to initiate the replication of lagging strand.

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