Answer :
Viral neutralization testing is based on the fact that viruses introduced into appropriate cell cultures have a cytopathic effect.
What is viral neutralization testing?
Virus neutralization tests are important because they can be used to determine the prevalence of disease, the geographical distribution of the virus, antibody titers in antisera, or the underlying principles of the immunological factors of infection. Known viruses can be used to detect specific antibodies, and known antibodies can be used to reveal the identity of viruses. This test is easy to use when significant amounts of antibodies are present. Antibodies are detected by adding a stock solution, such as serum containing the suspected antibody, to a suspension containing a known amount of virus. After varying contact times at specific temperatures, the mixture is injected into selected animal species by specific routes and monitored for viral impact (no neutralization) or no impact (no effect). B. neutralization). However, if the serum contains enough antibodies to neutralize
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