Streptococcus pneumoniae is a cause of pneumonia in children, and it has evolved mechanisms to protect itself from the effects of complement by binding factor H.
Complement is a group of proteins that play a role in the immune response. They are found in the blood and are part of the innate immune system. Complement proteins help to kill bacteria and other pathogens. S. pneumoniae has evolved mechanisms to protect itself from the effects of complement by binding factor H. This binding prevents the complement proteins from doing their job and results in the pathogen being able to survive and cause disease.
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