An environmental change can lead to the production of more than the expected amount of cyclin in g1. This would tend to _______ the activity of a cdk, which would lead to _______ phosphorylation of the target protein, which in turn would lead to _______ cells being stopped at the g1-to-s checkpoint.



Answer :

An alteration in the environment may cause g1 to produce more cyclin than is typical. As a result, there would be a tendency for a cdk to function less actively, which would result in less phosphorylation of the target protein, which would increase the number of cells that reach the g1-to-s checkpoint.

  • The production of cyclin/CDKs controls the progression of the cell cycle by phosphorylating the target genes, such as the tumor suppressor protein retinoblastoma (Rb).
  • Cyclins/CDKs are activated by mitogenic signals, but are blocked by the activation of cell-cycle checkpoints in response to DNA damage. The cyclin family of proteins controls how quickly a cell advances through the cell cycle by activating cyclin-dependent kinase (CDK) enzymes or a group of enzymes required for cell cycle synthesis.
  • Climate change, freshwater shortages, biodiversity loss (which impacts how ecosystems function), and fisheries weariness are a few examples of these environmental changes on a worldwide scale.
  • Although there are countless environmental issues, three in particular have the biggest effects on all of them: biodiversity loss, water pollution, and ocean acidification. People all throughout the world will be affected by its impacts, which include harsher weather, higher food prices, reduced options for recreation, and fewer opportunity to appreciate nature.

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