although the citric acid cycle itself does not use o2, it requires a functioning electron transport chain (which uses o2) in order to regenerate which molecule for further use in the citric acid cycle?

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04-11-2022
Chemistry

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although the citric acid cycle itself does not use o2, it requires a functioning electron transport chain (which uses o2) in order to regenerate which molecule for further use in the citric acid cycle?

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kjuli1766 kjuli1766 · Answer 1 · 2022-11-08T12:51:06-05:00

The molecule for further use in the citric acid cycle is NAD+.

In the absence of oxygen after glycolysis cells undergo fermentation without the citric acid cycle or oxidative phosphorylation. The citric acid cycle requires oxygen. This is because the electron transport chain requires an electron acceptor to regenerate her NAD, which is the role of oxygen.

Some of this is considered an aerobic pathway because the NADH and FADH2 produced must transfer electrons to the next pathway in the system using oxygen. Without oxygen, this transfer would not occur. Two carbon atoms from each acetyl group enter the citric acid cycle. Oxygen is the terminal electron acceptor of the mitochondrial electron transport chain and is therefore required for energy production via oxidative phosphorylation.

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