during transcription, the removal of histone proteins from the dna is important for group of answer choices the phosphorylation of ctd. the formation of the preinitiation complex. transcriptional elongation.

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04-11-2022
Biology

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during transcription, the removal of histone proteins from the dna is important for group of answer choices the phosphorylation of ctd. the formation of the preinitiation complex. transcriptional elongation.

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singhanupama3490 singhanupama3490 · Answer 1 · 2022-11-16T06:22:18-05:00

At the same time, histones are removed from DNA in vivo during intense transcription. Under these conditions, histone-free DNA could be available for binding to the transiently exposed octamer surface, increasing the likelihood of translocation of the nucleosomes remaining on the genes.

The ATP-dependent nucleosome remodelers and histone chaperones work together to facilitate the removal of histones from the DNA and their assembly onto the DNA.It is obvious that the absence of histones results in disorganized and ineffectively structured human genomic DNA. Furthermore, histone post-translational modifications (PTMs) play an important role in the regulation of nucleosome dynamics as well as a variety of DNA-related processes such as transcription, replication, and repair.

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