The maximum theoretical number of water molecules that one urea molecule can hydrogen bond with is 5.
Theoretically, there are a maximum of five water molecules that one urea molecule can hydrogen bond with, but there are 5 hydrogen bonds among one urea molecule and five molecules of water.
At this sort of excessive concentration, all water molecules are basically part of the solvation shell of a urea molecule, which consists of five to seven water molecules, as is known from molecular dynamics simulations (eleven).
It is miles determined that urea contains simply into the water, forming reported hydrogen bonds with water at both the amine and carbonyl headgroups. similarly the urea additionally hydrogen bonds to itself, forming chains or clusters which include as many as about 60 urea molecules in a cluster.
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