what is the relationship between the formation of ip3 and the elevation of intracellular [ca2 ]?

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31-10-2022
Biology

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what is the relationship between the formation of ip3 and the elevation of intracellular [ca2 ]?

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kjuli1766 kjuli1766 · Answer 1 · 2022-11-03T14:40:00-04:00

Phosphatidylinositol-specific phospholipase C-B produces second messengers derived from phosphatidylinositol-inositol triphosphate (IP3) and diacylglycerol (DAG). The IP3 receptor is a tetrameric Ca2+ channel.

Further, IP3Rs are able to extend Ca2+ signals from the lysosomes and, consequently, impact autophagic flux in response to lysosomal channels activation. furthermore, indirect modulation of Ca2+ release via IP3Rs may also be performed by controlling the Sarco/endoplasmic reticulum Ca2+ ATPases Ca2+ pumps of the ER.

Concerning calcium (Ca2+) signaling, it's far nicely mounted that IP3 produced via % activation diffuses into the cytosol and releases Ca2+ from in-https://brainly.com/question/25520896stores, selling intracellular calcium mobilization.

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