Epigenetics may be defined as changes in the expression of a gene or set of genes by DNA methylation and chromosomal protein alteration.
- DNA methylation is a heritable epigenetic mark that is created when DNA methyltransferases covalently add a methyl group to the DNA's cytosine ring at position C-5 (DNMTs). 1 Both symmetrical (CG or CHG) and asymmetrical (CHH, where H is A, T, or C) contexts are used to methylate cytosines in plants. Anywhere throughout the genome, cytosines are methylated in mammals.
- Disorders with varying degrees of complexity are caused by changes to chromosomes, genes, and proteins. For the purpose of identifying these illnesses, genetic testing is conducted. It enables us to comprehend the severity of the condition and whether it is heritable and can affect future generations. It helps in deciding how to proceed with treatment.
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