Answer: The membrane is hyperpolarized by it.
Fatigue happens when the amount of ATP available cannot keep up with the amount of ATP needed for exercise. The ATP/ADP ratio could be maintained by converting two molecules of ADP into one molecule of ATP and one molecule of AMP. AMP is then transformed into IMP and ammonia by the AMP-deaminase.
Acid lactate
Lactic acid is produced and accumulates in the muscle when there is a high energy demand, rapid changes in the energy requirement, and a lack of oxygen. During prolonged, intense activity, muscle pH falls to 6.4–6.6.
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