BPA is a chemical compound that was used in the manufacturing of plastic. When it comes into contact with cells, the cells mistake it for hormones that stimulate cell division. BPA is considered to increase the risk of certain cancers. Using knowledge of the cell cycle explain why and how this compound increases the risk of cancer?

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27-10-2022
Biology

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BPA is a chemical compound that was used in the manufacturing of plastic. When it comes into contact with cells, the cells mistake it for hormones that stimulate cell division. BPA is considered to increase the risk of certain cancers. Using knowledge of the cell cycle explain why and how this compound increases the risk of cancer?

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JuleK165548 JuleK165548 · Answer 1 · 2022-10-27T13:07:47-04:00

Research has shown that exposure to BPA can disrupt the functioning of the endocrine system. However, the levels of exposure in most people's daily lives are unlikely to result in serious harm. BPA has destructive effects on DNA and chromosomes in normal body cells via estrogen receptors (ER). Therefore, BPA could be considered as an important mediator in many diseases such as cancer. he toxic chemical has been linked to causing reproductive, immunity, and neurological problems, as well as an increased likelihood of Alzheimer's, childhood asthma, metabolic disease, type 2 diabetes, and cardiovascular disease.

BPA can mimic estrogen to interact with estrogen receptors α and β, leading to changes in cell proliferation, apoptosis, or migration and thereby, contributing to cancer development and progression.