Answer :
The killing of infected target cells by effector CD8 T cell is initiated by CD4 molecule molecular interaction at the surface of cells.
In the host's defense against pathogens that dwell in the cytosol, the most prevalent of which are viruses, armed effector cytotoxic CD8 T cells are crucial.
These cytotoxic T cells can destroy any pathogen-carrying cell by identifying foreign peptides that are carried to the cell surface in an MHC class I molecule-bound manner.
Because killer T cells have unique molecular weapons that allow them to attack and completely destroy other cells showing targets they recognize, such as a virus-infected cell or even a malignant cell, they are known as "cytotoxic" or "cytolytic" cells.
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