The fundamental distinction between EPSP and an action potential is that an action potential's magnitude diminishes as it passes along the membrane. EPSPs arise in the absence of sodium ions entering the cell.
- An excitatory postsynaptic potential is a postsynaptic potential that increases the likelihood of a postsynaptic neuron firing an action potential. An excitatory postsynaptic potential (EPSP) is a transient depolarization of the postsynaptic membrane generated by the entry of positively charged ions into the postsynaptic cell via ligand-sensitive channels.
- An action potential is generated when a neuron sends information down an axon away from the cell body. The action potential is referred to by neuroscientists as a "spike" or a "impulse." A depolarizing current causes an electrical activity explosion, which causes the action potential.
Thus this is the difference between EPSP and action potential.
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