Activators are transcription factors that bind to the enhancer region of DNA. These catalysts are also known as proteins.
As described below, TFs, coregulators, chromatin modifiers, architectural proteins including Cohesin, Condensin, and CTCF, other enzymes, and RNAPII bind to enhancers, which are composed of dense clusters of transcription factor binding sites (TFBS).
The majority of activators are DNA-binding proteins that interact with the promoter- or enhancer-proximal components. An "activator-binding site" is the DNA site that the activator binds to.
RNA polymerase binds to a portion of a gene's DNA known as the promoter to start transcription of the gene. The promoter essentially instructs the polymerase to "sit down" on the DNA and start transcription.
The transcription factors known as activators bind to the enhancer region of DNA. Protein is another name for these activators.
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