Compared to the mitochondrial intermembrane space, the mitochondrial matrix could be described as having higher pH and lower pyruvate concentration.
Despite only about 5% of the mitochondrial proteome, the mitochondrial intermembrane space (IMS) is the most restricted sub-mitochondrial compartment and has the widest variety of protein import pathways.
IMS-localized proteins do not need energy sources like ATP hydrolysis in the mitochondrial matrix or the inner membrane electrochemical potential, which are essential for import into the matrix or insertion into the inner membrane, as they need to cross the outer mitochondrial membrane.
Numerous proteins in the mitochondrial intermembrane space (IMS) lack the conventional mitochondrial targeting signals. They are imported using a distinct mechanism independent of the inner membrane potential and ATP hydrolysis.
Learn more about mitochondria here:
https://brainly.com/question/1619743
#SPJ4