Answer :
Based on the observations made by Hodgkin and Huxley, one can expect ion channels to allow ions to move across the membrane quickly, work with the electrochemical gradients, exist in distinct variants, and respond to changes in the membrane potential.
So, the correct option is E.
Hodgkin and Huxley showed that during an action potential, the membrane potential of the neuron actually flips, leading the cell to briefly have a positive membrane potential. The action potential's electrical signal was created as a result of the membrane potential's quick reversal. In neurons, muscles, and other excitable cells, voltage-gated sodium channels start action potentials. Hodgkin and Huxley used the voltage-clamp technique in their seminal series of studies from 1952 to identify the sodium current that starts the nerve action potential.
The conceptual foundation for at least three levels of neuroscience study was established by the Hodgkin-Huxley model, which is significant. The Hodgkin-Huxley model first developed a framework for describing the structural and functional characteristics of ion channels, including the mechanisms of ion permeation, selectivity, and gating, at the molecular level.
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