Answer :
Option A is the correct answer. a) A protein that enters the nucleus to bind with DNA is not made at the rough endoplasmic reticulum.
The protein that enters the nucleus to bind with DNA will not have the rough endoplasmic reticulum. Because the rough endoplasmic reticulum present in the nucleus will have the proximity which gives the rough endoplasmic reticulum control over the protein processing.
The Rough endoplasmic reticulum can able to send signals to the nucleus if there is any problem in the synthesis of protein which increases the total rate of translation of the proteins.
Whereas the other proteins such as insulin ( a secreted proteinaceous hormone), a digestive enzyme of the gut, and the collagen from the extracellular matrix will make at the rough endoplasmic reticulum.
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