Answer :
The best method to sterilize heat-liable solution is Membrane filtration
Membrane filtration method is the best method to sterilize heat-liable solutions. Heat-liable solution means the object or thing that is susceptible for destruction or alternations at extreme temperature.
Membrane filtration method will have many filtration level filters with decreasing pore size to the level of 0.45 μm. Thus if any heat-liable solutions poured on the membrane filters will pass through many membranes and the micro-organisms which are larger than size of 0.45μm will be trapper by this technique. It will not involve any change in temperature. Thus , it is the best method to sterilize the heat-liable solution.
Whereas Freezing , Dry heat and Autoclave will changes the temperature of the solution to both ends (Hot and cold).
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