Measles is a viral disease. Symptoms of measles infection include a fever, a runny nose, and a rash. The replication process used by the measles virus results in the rapid destruction of the infected cell. This process is known as.

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25-10-2022
Biology

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Measles is a viral disease. Symptoms of measles infection include a fever, a runny nose, and a rash. The replication process used by the measles virus results in the rapid destruction of the infected cell. This process is known as.

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rafikiedu08 rafikiedu08 · Answer 1 · 2022-11-04T11:52:24-04:00

Measles is a viral disease. Symptoms of measles infection include a fever, a runny nose, and a rash. The replication process used by the measles virus results in the rapid destruction of the infected cell. This process is known as apoptosis.

It is known that many viruses create cellular compartments, sometimes known as viral factories. Measles virus and other paramyxoviruses colocalize their genomic and proteomic components in puncta within infected cells. We show that when mixed together in vitro, the pure nucleoproteins (N) and phosphoproteins (P) of the measles virus create liquid-like membraneless organelles. We find weak interactions, one of which is crucial for phase separation, involving inherently disordered regions of N and P. While NMR is utilized to explore the thermodynamics of this process, fluorescence enables us to monitor the change of the dynamics of N and P following droplet formation.When RNA and droplets colocalize, the assembly of N protomers into nucleocapsid-like particles, which encapsidate the RNA, is triggered. One of the functions of liquid-liquid phase separation in measles virus replication is revealed by the increased rate of encapsulation within droplets compared to the dilute phase.

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